![Splice is Thought-Provoking, Disturbing Sci-Fi Horror [The Rabid Dog’s House]](http://wickedhorror.com/wp-content/uploads/2025/06/Splice-Sarah-Polley-Dren-Cover.png "Splice is Thought-Provoking, Disturbing Sci-Fi Horror [The Rabid Dog’s House]")
The Rabid Dog’s House is a recurring feature at Wicked Horror where contributor Justin Steele uncovers hidden gems, lost classics, and overlooked indie offerings with a little bite. Flying solo or with his co-host Zena Dixon, he will discuss an array of topics covering film, literature, and television. Check out the latest installment below. In this episode we’re looking back at 2009 Splice!
Splice is directed by Vincenzo Nitali and stars Sarah Polley, Adrien Brody, Delphine Chaneac, and David Hewlett. Clive (Brody) and Elsa (Polley) are genetic engineers on the verge of global fame. Although they are instructed to stop any further progress on their latest controversial project, the two genetic engineers decide to proceed in secret. Their latest project is named Dren (Chaneac). She is groundbreaking, controversial, and unfortunately for Clive and Elsa, has a mind of her own. Initially amazed by Dren’s abilities, the relationship between Elsa and Clive begins to splinter as day by day the scientists lose control over their creation.
Related: Remembering Pin (1988) [The Rabid Dog’s House]
Led by brave performances from Sarah Polley and Adrien Brody, this 2009 flick is as fascinating as it is shocking. At the same time, the themes of this film are just as controversial and relevant today. Splice is for the horror fan that enjoys science fiction horror with a hip, modern edge.
![Jim Burns talks illustrating Folio Society’s IT [Exclusive]](https://wickedhorror.com/wp-content/uploads/2025/07/ITSK_S_12-1.jpg "Jim Burns talks illustrating Folio Society’s IT [Exclusive]")
